儿童患B型流感导致的急性瘤性脑炎:一个病例报告
Prashant Kumar Singh1, Rohit Sharma2, Chanakya Saini3
1Child Neurology, University of Florida Health, Gainesville, USA.
Cureus
|June 8, 2023
概括
本案例研究详细介绍了一个罕见的流感B相关的急性死脑炎 (ANE) 在一个8岁的孩子,以大脑和尾巴马参与. 尽管进行了积极的治疗,但该患者经历了严重的神经缺陷.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 儿科 儿科 儿科
背景情况:
- 急性死性脑炎 (ANE) 是一种严重的神经疾病,通常与病毒感染有关,并以迅速发病为特征.
- 细胞因子风暴与ANE的发病有关,导致大脑广泛炎症.
- 流感病毒,特别是B型流感,是已知的,尽管不常见的,但是ANE的原因.
研究的目的:
- 在儿科患者中报告一种独特的B型流感相关NEE病例.
- 要突出尾巴马在ANE中的参与,这是以前没有报道的发现.
- 讨论这种罕见疾病的临床表现,神经成像发现和治疗结果.
主要方法:
- 一个八岁的女性患者的病例报告.
- 临床评估包括神经学检查和快速恶化.
- 大脑和脊椎的磁共振成像 (MRI).
- 对诊断和治疗方案的审查.
主要成果:
- 患者出现了B型流感感染和快速进展的神经症状.
- 核磁共振扫描显示了多焦点大脑病变,影响小脑和脑干,以及模仿Guillain-Barre综合征的尾牙炎症.
- 尽管用奥塞尔塔米维尔,类固醇和静脉注射免疫球蛋白治疗,但该患者的神经结果不佳.
结论:
- 这是第一个报告的ANE病例,同时涉及cauda equina.
- 乙型流感会对儿童造成严重的,广泛的神经损伤,包括对外围神经系统的干扰.
- 即使有迅速和全面的治疗,ANE的预后仍然很差.
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