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恶心是与儿科功能性消化不良患者的胃空气延迟相关的唯一症状
Marijke De Keukelaere1, Florencia Carbone2,3, Karen van Hoeve4
1Pediatric Department, Imelda Hospital Bonheiden and University Hospitals Leuven, Leuven, Belgium.
Neurogastroenterology and motility
|June 8, 2023
概括
儿童的功能性消化不良 (FD) 与胃排空 (GE) 测试结果有关. 延迟的GE与恶心增加有关,这表明对具有恶心症状的FD进行GE测试.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 功能性胃肠道疾病 功能性胃肠道疾病
- 消化系统生理学 消化系统生理学
背景情况:
- 功能性消化不良 (FD) 是儿童常见且复杂的功能性胃肠道疾病 (FGID).
- FD呈现出各种上部胃肠道症状,影响生活质量.
- 了解生理基础,如胃空化 (GE),对于有效的管理至关重要.
研究的目的:
- 为了研究功能性消化不良 (FD) 和胃空虚 (GE) 症状之间的关系,在儿科患者中进行呼吸测试结果.
- 为了确定延迟的GE是否与儿童的特定FD症状严重程度相关.
- 评估GE呼吸测试在儿科FD的诊断工作中的实用性.
主要方法:
- 一组患有消化不良症状 (罗马第四标准) 的儿童 (6-17岁) 接受了13C-八酸GE呼吸测试.
- 在240分钟的时间内,使用验证的图形图表和问卷评估消化不良症状的严重程度.
- 包括曼-惠特尼测试在内的统计分析比较了正常和延迟GE组之间的症状得分.
主要成果:
- 在39名FD患者中,43%的人表现出延迟GE.
- 在正常和延迟GE的儿童之间,整体症状严重程度没有显著差异.
- 恶心是延迟GE组中唯一明显更严重的个体症状 (p=0.048).
结论:
- 在患有FD的儿童中,延迟胃排空主要与恶心增加有关.
- 对于患有恶心的儿科FD患者,建议进行GE呼吸测试的低门.
- 基因呼吸测试可以提供宝贵的见解,对儿童的FD的病理生理学,特别是当恶心是突出的.
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