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Updated: Jul 27, 2025

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

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C-终端β8-α9相互作用调节热稳定性和酶活性在高热友雌激酶EstE1和中热友雌激酶rPPE中不同

Tu Anh Nguyen1, Sei-Heon Jang1, ChangWoo Lee1

  • 1Department of Biomedical Science and Center for Bio-Nanomaterials, Daegu University, Gyeongsan, South Korea.

Applied and environmental microbiology
|June 8, 2023
PubMed
概括

这项研究揭示了酶如何使用疏水相互作用或键来保持稳定性和活性. 虽然这两种相互作用都同样有助于热稳定,但键增强了酶中的催化活性.

关键词:
一个模块化界面 (dimer) 界面埃斯特拉酶的使用方法通过键结合,形成键.疏水性相互作用 疏水性相互作用温度适应 温度适应α/β-酸盐化剂

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