基于社区和基因组的证据表明,氧化还原潜力对细菌蛋白质进化的影响
1Key Laboratory of Metallogenic Prediction of Nonferrous Metals and Geological Environment Monitoring of Ministry of Education, School of Geosciences and Info-Physics, Central South University , Changsha, China.
mSystems
|June 8, 2023
概括
氧化还原条件影响微生物基因组的进化. 细菌群落中的蛋白质序列与环境氧化还原潜力呈正相关性,这表明地质化学塑造了基因组组成.
科学领域:
- 微生物生态学 微生物生态学
- 地质化学 地质化学
- 基因组学就是基因组学.
背景情况:
- 了解环境因素如何塑造微生物群落至关重要.
- 氧化还原条件对微生物基因组序列组成的影响在很大程度上仍未知.
- 环境地质化学可能在微生物进化和生物地理学中发挥作用.
研究的目的:
- 研究微生物基因组中蛋白质序列的氧化还原条件和碳氧化状态 (ZC) 之间的相关性.
- 确定地球化学是否调节细菌和古生物的基因组进化.
- 为了测试微生物群落的化学适应假设,通过氧化还原梯度.
主要方法:
- 利用68个公开的16S rRNA基因序列数据集来估计微生物基因组丰度.
- 分析了社区参考蛋白质的碳氧化状态 (ZC).
- 相关ZC与氧化还原潜力 (Eh) 纠正到pH7 (Eh7) 在不同的环境.
主要成果:
- 在大多数环境中,细菌群体在当地和全球都表现出了ZC和Eh7之间的正相关性.
- 考古社区显示出混合的相关性,只有当考虑氧气度时,才会出现积极的泛环境相关性.
- 经验证据表明,地球化学调节了基因组进化,对细菌和古生物有明显的影响.
结论:
- 地质化学因素,特别是氧化还原条件,显著影响微生物基因组的元素组成.
- 基因组进化可能使蛋白质序列能够在数百万年内适应它们的化学环境.
- 热力学模型可以提供关于微生物社区组装和进化的地化学影响的见解.
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