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"外周 perfusion 指数区分血液动力学反应诱导全身麻醉"

Jakob Højlund¹, David René Petersen^2,3, Marianne Agerskov²

¹Department of Anaesthesiology, Hvidovre University Hospital, Capital Region, Denmark. jakob.hoejlund@regionh.dk.

Journal of clinical monitoring and computing

|June 8, 2023

概括

周围输液指数 (PPI) 可以在全身麻醉诱导期间非侵入性监测血液动力学变化. PPI的变化有效地反映了血压,中风量和心脏输出量的减少,表明其作为简单的血液动力学指标的潜力.

科学领域:

麻醉学麻醉学
心血管生理学心血管生理学
医疗监测医疗监测

背景情况:

一般麻醉诱导通常会导致低血压.
标准的血液动力学监测采用间歇性测量,限制了实时循环评估.
持续的全身血压监测通常需要侵入性或先进的方法.

研究的目的:

调查周围输液指数 (PPI) 的变化是否反映了在全身麻醉诱导期间的全身血动力学变化.
确定PPI作为诱导后血液动力学状态的非侵入性指标的潜力.

主要方法:

在107名手术患者中,持续监测PPI,中风体积 (SV),心脏输出量 (CO) 和平均动脉压 (MAP).
在麻醉诱导后2分钟内,SV,CO和MAP的相对变化与PPI变化的比较.
采用了微创和非创监测技术.

主要成果:

在诱导后,MAP,SV和CO在整个队列中显著下降.
与PPI增加的患者相比,PPI降低的患者显示MAP,SV和CO的减少更大.
PPI的变化有效地区分了不同程度的血液动力学减少 (p < 0.001).

结论:

周围输液指数 (PPI) 的变化与全身血动力学变化在全身麻醉诱导期间相关联.
PPI作为一种潜在的简单,非侵入性指标,用于评估诱导后的血液动力学变化.
这一发现可能会改善麻醉中实时心血管监测.

关键词:

循环监控是指循环的监控.整体麻醉整体麻醉诱导期是一个诱导期.非侵袭性监测是一种非侵袭性监测.周边 perfusion 指数是指周边 perfusion 指数是指周边 perfusion 指数是指周边 perfusion 指数.

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