大麻效果预期问卷-医学 (CEEQ-M):临床试验中的初步心理测量特性和纵向验证
Jakob H Weiss1, Brenden Tervo-Clemmens1, Kevin W Potter1
1Department of Psychiatry, Center for Addiction Medicine, Massachusetts General Hospital.
Psychological assessment
|June 8, 2023
概括
大麻预期并没有预测医用大麻患者的症状缓解或使用变化. 然而,较高的基线大麻使用预测了更积极的预期变化,这表明CEEQ-M工具是可靠的.
科学领域:
- 心理学 心理学 心理学
- 药理学 药理学是指药理学的学科.
- 大麻研究 大麻研究
背景情况:
- 医用大麻的使用量正在上升,但对疗效的证据有限.
- 患者对大麻的期望可能会影响大麻对症状的影响.
- 以前的研究没有检查大麻预期预测症状缓解.
研究的目的:
- 引入和验证大麻效果预期问卷-医学 (CEEQ-M).
- 评估大麻预期的症状缓解和在医用大麻患者中使用的预测价值.
- 在纵向研究中检查CEEQ-M的心理特征.
主要方法:
- 开发和验证21项CEEQ-M.的发展和验证
- 长度随机临床试验涉及269名成年人.
- 交叉滞后的面板模型分析了3个月和12个月的期望,大麻使用和症状 (疼痛,失眠,焦虑,抑郁症).
主要成果:
- 该CEEQ-M表现出良好的心理测量特性,包括因子结构和测量不变性.
- 大麻预期没有预测自我报告的大麻使用或症状严重程度的变化.
- 较高的基线大麻使用预测了随着时间的推移对期望的更积极的变化.
结论:
- CEEQ-M是评估医用大麻预期的心理测量标准.
- 目前的发现表明,预期可能无法预测短期的症状缓解或使用变化.
- 未来的研究应该探索医用大麻期望的时间动态和分歧.
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