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人类肝酶的高分辨率结构组学

Chih-Chia Su1, Meinan Lyu1, Zhemin Zhang1

  • 1Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Cell reports
|June 8, 2023
PubMed
概括

低温电子显微镜揭示了十种人类肝酶的原子结构,包括H6PD和GANAB. 这种技术有助于我们更好地理解人体器官蛋白质组学和酶功能.

关键词:
CP:新陈代谢过程中的新陈代谢.科普:分子生物学 分子生物学阿尔德海德氧化酶 1碳氧乙酶 1 的作用.葡萄糖酶II的使用方法谷氨酸脱酶1的使用方法糖原酸化酶的使用方法赫索索-6-酸盐脱酶的使用微小的三糖转移蛋白质复合体.过氧化素 4 细胞内网膜蛋白 46 复合物视网甲脱酶 1 的作用.结构经济学 结构经济学

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The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
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