关联的25 ((OH) -维生素D和代谢因素与结直肠多
Chih-Hsiang Chiang1, Yu-Jun Chang2, Sin-Ru He1
1Department of Family Medicine, Changhua Christian Hospital, Changhua, Taiwan.
PloS one
|June 8, 2023
概括
维生素D缺乏与患结直肠多瘤 (CRPs) 的风险更高有关,特别是在老年人和女性中. 诸如高血糖和高甘油三等代谢因素也会增加CRP的风险.
科学领域:
- 内分泌学 在内分泌学.
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 已知维生素D在癌症中的作用,但其与结直肠息肉 (CRPs) 的联系尚不清楚.
- 这项研究研究了维生素D,代谢因素和CRPs.
研究的目的:
- 检查维生素D水平,代谢因素和结直肠多的风险之间的关联.
- 为了确定CRPs和腺多的特定风险因素.
主要方法:
- 在台湾对1306名参与者 (2017-2019) 的横截面研究.
- 结肠镜用于CRP诊断和病理学分析.
- 逻辑回归用于分析关联.
主要成果:
- 维生素D缺乏和CRPs的患病率分别为21.21%和40.89%.
- 与年龄较大,男性性别,高血糖,高甘油三和低维生素D相关的CRP风险增加.
- 低维生素D与女性的CRPs相关;男性的血压升高.
结论:
- 维生素D缺乏会显著增加CRP的风险,特别是在50岁以上的成年人和女性中.
- 代谢综合征的组成部分 (高血糖,男性高血压,高甘油三) 是关键问题.
- 强调监测维生素D和代谢健康对于预防CRP的重要性.
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