Mslar:微生物合成致命和救援数据库
Sen-Bin Zhu1,2, Qian-Hu Jiang1, Zhi-Guo Chen1
1School of Life Science and Technology, Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China.
PLoS computational biology
|June 8, 2023
概括
合成致死性 (SL) 和合成救援 (SR) 基因对对了解微生物遗传学至关重要. 我们开发了微生物合成致命和救援数据库 (Mslar),以对这些相互作用进行分类,帮助研究人员.
科学领域:
- 微生物遗传学微生物遗传学
- 系统生物学 系统生物学
- 基因组学就是基因组学.
背景情况:
- 合成致命性 (SL) 是一种遗传相互作用,其中两个基因的突变导致细胞死亡,但不是单一的突变.
- 预测SL基因对的现有方法主要集中在酵母和大肠杆菌等模型生物上.
- 缺乏微生物SL和合成救援 (SR) 基因对的集中资源.
结论:
- 马斯拉作为微生物遗传学研究的宝贵参考.
- 该数据库有助于研究微生物中的合成致死性和救援相互作用.
- Mslar是研究界在线免费访问的.
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