生命历程心血管健康:风险因素,结果和干预措施
Havisha Pedamallu1, Rachel Zmora2, Amanda M Perak2,3
1Division of Internal Medicine, Department of Medicine (H.P.), Northwestern University Feinberg School of Medicine.
Circulation research
|June 8, 2023
概括
从生命早期保持最佳的心血管健康 (CVH) 是至关重要的. 儿童CVH预测成人健康结果,强调早期干预和个性化预防策略的必要性.
科学领域:
- 心血管健康研究 心血管健康研究
- 生命历程流行病学 流行病学
- 预防性心脏病学 预防性心脏病学
背景情况:
- 2010年由美国心脏协会定义的心血管健康 (CVH) 被研究了整个生命过程.
- 产前和儿童期的暴露与从童年到成年期的CVH轨迹有关.
- 在任何生命阶段的CVH预测未来的心血管疾病,痴呆症,癌症,死亡率和其他健康结果.
研究的目的:
- 审查关于CVH早期生命预测因素的文献.
- 检查儿童CVH的后期生活结果.
- 确定在不同人群中促进CVH的干预.
主要方法:
- 关于心血管健康预测因素,结果和干预措施的研究文献综述.
- 对研究分析,将早期生命暴露与CVH轨迹联系起来.
- 综合关于CVH对长期健康的预测价值的研究结果.
主要成果:
- 产前和儿童期的暴露总是可以在整个生命周期内预测CVH.
- CVH是主要疾病和死亡率的强有力的预测指标.
- 干预并不频繁,通常针对多个基于社区的风险因素,很少集中在儿童身上.
结论:
- 早期干预对于预防CVH损失和心血管风险积累至关重要.
- 未来的研究需要有效的,可扩展的,可持续的干预,利用技术和实施科学.
- 社区参与和个性化预防策略对于促进理想的CVH终身至关重要.
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