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Updated: Jul 27, 2025

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在Salpingo-Oophorectomy之后,携带BRCA1和BRCA2致病变体的携带者骨密度的变化

Leslie N Chan1, Lee-May Chen, Mindy Goldman

  • 1School of Medicine, the Department of Obstetrics, Gynecology and Reproductive Sciences, the Helen Diller Family Comprehensive Cancer Center, the Department of Medicine, and the Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, San Francisco, California; the Division of Gynecology Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Facing Our Risk of Cancer Empowered, Tampa, Florida.

Obstetrics and gynecology
|June 8, 2023
PubMed
概括

在34-50岁的BRCA1/2携带者中,降低风险的卵管切除术 (RRSO) 与卵巢保护相比,导致显著的骨损失. 激素治疗可以减轻但不能消除这种骨损失.

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