活着的人类婴儿下肢的三维骨肌肉结构
Brian V Y Chow1, Catherine Morgan2, Caroline Rae3
1Neuroscience Research Australia (NeuRA), Sydney, NSW, Australia; School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
Journal of biomechanics
|June 8, 2023
概括
这项研究使用MRI和DTI来绘制婴儿下腿肌肉的图表,揭示了中间胃肌肉比横向肌肉更大. 婴儿肌肉生长主要是增加截面,而不是长度,在成年之前.
科学领域:
- 人类解剖学 人类解剖学
- 发展生物学 发展生物学
- 生物医学成像技术 生物医学成像技术
背景情况:
- 新生儿的骨肌结构在很大程度上没有特征.
- 了解婴儿肌肉发育对于儿科研究至关重要.
研究的目的:
- 为了研究活着的人类婴儿的3D骨肌结构.
- 为了比较中间和侧面的胃角肌肉之间的肌肉特性.
- 将婴儿肌肉发育与成人数据进行比较.
主要方法:
- 使用磁共振成像 (MRI) 测量婴儿 (<3个月) 下腿肌肉体积.
- 结合MRI与扩散张力成像 (DTI) 进行高分辨率3D重建.
- 测量时刻臂,束子长度,生理横截面积 (PCSA) 和笔纹角.
主要成果:
- 婴儿下腿肌肉总体体积平均为29.2厘米3;soleus是最大的肌肉.
- 中部胃角肌 (MG) 的体积 (~35%) 和PCSA (~63%) 比侧部胃角肌 (LG) 的体积更大.
- 与婴儿相比,成年人MG肌肉的体积 (63倍),PCSA (36倍) 和带长度 (1.7倍) 显著增加.
结论:
- 核磁共振和DTI对于婴儿骨肌结构分析是可行的.
- 婴儿MG肌肉束从婴儿到成年时主要以横截面而不是长度增长.
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