初潮的早期年龄是否与多种疾病相关? 来自阿扎尔队列研究的发现
Amin SadrAzar1, Sarvin Sanaie2, Helda Tutunchi3
1Liver and Gastrointestinal Diseases Research Center of Tabriz University of Medical Sciences. Tabriz, Iran.
概括
初潮时的早期或晚年 (AAM) 与各种慢性疾病有关. 了解这些关联对于制定有效的青少年和年轻成人健康策略至关重要.
科学领域:
- 生殖健康 生殖健康
- 流行病学 流行病学
- 慢性疾病研究研究.
背景情况:
- 初潮时的年龄 (AAM) 是一个重要的生殖里程碑.
- 新出现的证据表明,AAM可能会影响长期的健康结果.
- 了解AAM和慢性疾病之间的联系对于公共卫生至关重要.
研究的目的:
- 调查初潮时的年龄 (AAM) 与多病症和慢性疾病的患病率之间的关联.
- 为了确定与早期 (<12岁) 和晚期 (>14岁) AAM相关的特定慢性疾病.
主要方法:
- 分析了阿扎尔队列研究中8,294名女性参与者的生殖史数据.
- 通过人口统计,生殖史,行为和社会经济地位的调查问卷收集的数据.
- 对AAM类别 (早期,正常,晚期) 与慢性疾病患病率进行统计分析.
主要成果:
- 早期AAM (<12岁) 与糖尿病,肥胖和高腰部至部比率 (WHR) 的风险增加相关.
- 晚期AAM (>14年) 与更高的高血压,中风和糖尿病率有关.
- 晚期AAM也与多重疾病,类风湿性疾病,肥胖,腹部肥胖和腰与身高比率 (WHtR) 的风险降低有关.
结论:
- 初潮时的年龄显著影响健康和慢性疾病的风险.
- 青少年和年轻人的预防健康策略应该考虑影响AAM的因素.
- 对初潮早期的后果进行进一步的研究对于有针对性的干预措施至关重要.
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