胸腔淋巴腺病在COVID-19中的临床重要性
Hans-Jonas Meyer1, Bohdan Melekh2, Andreas Wienke3
1Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Journal of infection and public health
|June 8, 2023
概括
通过CT扫描识别的胸腔淋巴腺病与2019年新冠肺炎 (COVID-19) 患者30天死亡风险更高有关. 淋巴结尺寸增加和受影响的区域表明预后较差.
科学领域:
- 医疗成像医学成像
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 胸腔淋巴腺病在COVID-19中的预后价值是不确定的.
- 计算机断层扫描 (CT) 可以揭示COVID-19患者的胸腔淋巴腺病变.
研究的目的:
- 在CT上分析受影响的淋巴结站和累积的淋巴结大小.
- 使用这些CT衍生的指标,预测COVID-19患者的30天死亡率.
主要方法:
- 177名COVID-19患者 (2020-2022) 的回顾性分析.
- 胸腔淋巴腺病症定义为短轴直径>10毫米.
- 累积淋巴结大小的计算和受影响的淋巴结站的量化.
主要成果:
- 53名患者 (29.9%) 在30天内死亡.
- 130名患者 (73.4%) 患有淋巴腺病.
- 没有幸存者的淋巴结受影响水平显著增加 (4.0对2.2),累积淋巴结尺寸更大 (55.9毫米对44.1毫米).
- 淋巴腺病的存在与30天死亡率的增加有关 (OR = 2.99,p = 0.02).
结论:
- 胸腔淋巴腺病变,通过CT大小和受影响水平来评估,预测COVID-19的30天死亡率.
- 患有胸腔淋巴腺病症的COVID-19患者是高危人群.
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