撒哈拉以南非洲地区疫苗信心的下降趋势:一项大规模的横截面建模研究
A de Figueiredo1, E Temfack2, R Tajudeen2
1Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Human vaccines & immunotherapeutics
|June 8, 2023
概括
在全球范围内,常规儿童免疫覆盖率正在下降,在非洲出现了显著下降. 这项研究发现,在2020年至2022年期间,八个撒哈拉以南国家的疫苗信心下降,特别是COVID-19疫苗的信心下降.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 全球常规儿童免疫覆盖率显示了30年来最大的持续下降,非洲出现了重大挫折.
- 虽然COVID-19大流行导致供应和交付中断,但其对疫苗信心的影响仍然不太清楚.
- 了解疫苗信心对于重建免疫系统和为未来的疫苗接种策略提供信息至关重要.
研究的目的:
- 从2020年到2022年,检查八个撒哈拉以南非洲国家的疫苗信心趋势.
- 评估COVID-19大流行对疫苗重要性,安全性和有效性的看法的影响.
- 在国家和次国家层面确定疫苗信心的社会人口统计学关联.
主要方法:
- 这是一项涉及8个撒哈拉以南国家的17187个个人访谈的跨界研究.
- 多阶段概率抽样和贝叶斯数据评估方法.
- 多级回归与分层化后权重使用当地人口统计数据来估计疫苗信心.
主要成果:
- 在所有八个国家都观察到,对儿童的疫苗的重要性有所下降.
- 2020年至2022年期间,在八个国家中,六个国家对COVID-19疫苗安全性和重要性的看法下降了.
- 在刚果民主共和国和南非,疫苗信心显著下降,具体区域差异.
- 在60岁以上的个体中观察到更高的疫苗信心,但没有其他个人社会人口因素与信心有显著的关联.
结论:
- COVID-19大流行对撒哈拉以南非洲地区的疫苗信心产生了负面影响,影响了对常规儿童疫苗和COVID-19疫苗的看法.
- 需要有针对性的战略来解决疫苗信心下降的问题,特别是在刚果民主共和国和南非等脆弱地区.
- 进一步研究疫苗犹的具体驱动因素和干预措施的有效性对于加强免疫计划至关重要.
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