Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Improving Translational Accuracy02:07

Improving Translational Accuracy

11.7K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
11.7K
Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

11.0K
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
11.0K
Synthetic Biology02:55

Synthetic Biology

4.9K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
4.9K
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

18.9K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.9K
Membrane Domains01:18

Membrane Domains

5.5K
The membrane domains concentrate specific lipids and proteins at one place within the membrane, which helps in cell signaling, adhesion, and other critical cellular processes. These domains can differ in size, composition, function, and lifespan.
Protein Domains
The membrane comprises a group of distinct proteins responsible for carrying out a cell's specific function. For example, the plasma membrane of the human sperm, or a single germ cell, contains a unique set of proteins in the...
5.5K
Conservation of Protein Domains02:26

Conservation of Protein Domains

3.1K
3.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Impact of modifiable lifestyle factors on dementia subtypes and brain structural changes across KDIGO risk categories in the UK biobank.

Brain imaging and behavior·2026
Same author

Association of Weight-Adjusted-Waist Index With Brain Health: A 16-Year Population-Based Longitudinal Cohort Study.

CNS neuroscience & therapeutics·2026
Same author

Low-substrate nitrogen drives functional succession toward a cooperative Candidatus Brocadia consortium in anammox systems.

Bioresource technology·2026
Same author

Associations of clinical obesity with arterial stiffness and cerebral small vessel disease: a population-based study.

Frontiers in endocrinology·2026
Same author

Luteolin ameliorates cigarette smoke-induced chronic obstructive pulmonary disease by modulating gut and lung microbiota and amino acid metabolism in C57Bl/6 mice.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Lotus-derived protein-rich nanoparticles relieve inflammatory bowel disease by modulating gut microbiota and bile acid metabolism.

International journal of biological macromolecules·2026

相关实验视频

Updated: Jul 27, 2025

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K

将生物医学文本分析领域的知识整合到深度学习中:一项调查

Linkun Cai1, Jia Li2, Han Lv2

  • 1School of Biological Science and Medical Engineering, Beihang University, 100191 Beijing, China.

Journal of biomedical informatics
|June 8, 2023
PubMed
概括

本综述探讨了将域名知识与生物医学文本分析的深度学习相结合. 结合知识图可以增强深度学习模型,克服数据限制,获得更好的洞察力.

关键词:
生物医学文本分析深度学习是一种深度学习.域名知识 域名知识自然语言处理自然语言处理.

更多相关视频

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

348
Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.2K

相关实验视频

Last Updated: Jul 27, 2025

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

348
Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.2K

科学领域:

  • 生物医学自然语言处理
  • 人工智能在医学中的应用
  • 知识表示和推理.

背景情况:

  • 生物医学领域已经看到文本数据的激增,这对医疗保健和研究至关重要.
  • 深度学习在生物医学文本分析方面表现有前途,但在数据注释和可解释性方面面临挑战.
  • 整合领域知识,就像生物医学知识图一样,为增强深度学习模型提供了解决方案.

研究的目的:

  • 综合审查最近关于将领域知识纳入生物医学文本分析的深度学习的文献.
  • 确定从这种整合中受益的常见生物医学文本分析任务.
  • 讨论这个跨学科领域当前的挑战和未来的研究方向.

主要方法:

  • 系统的文献搜索,重点关注过去十年内发表的研究.
  • 分析了150多篇研究论文.
  • 根据所处理的生物医学文本分析任务对研究进行分类 (例如,信息提取,文本分类,文本生成).

主要成果:

  • 域知识的整合,特别是生物医学知识图,是生物医学NLP深度学习的日益增长的趋势.
  • 这种方法有效地解决了数据稀缺的局限性,并提高了模型的可解释性.
  • 关键应用包括增强信息提取,更准确的文本分类,以及改善生物医学领域的文本生成.

结论:

  • 将领域知识纳入深度学习模型是推动生物医学文本分析的强大策略.
  • 未来的研究应该专注于开发更复杂的知识整合方法,并解决可解释性和可扩展性的剩余挑战.
  • 这种跨学科的方法具有加速生物医学发现和改善医疗保健结果的巨大潜力.