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Updated: Jul 27, 2025

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Y盒结合蛋白1促进染色质的可访问性,使肝纤维化恶化

Zihui Tang1, Bowen Lin2, Wei Li3

  • 1Department of Gastroenterology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.

Cellular signalling
|June 8, 2023
PubMed
概括

Y盒结合蛋白1 (YBX1) 通过增加染色质可访问性和激活纤维生成基因,加剧肝纤维化. 减少YBX1的表达改善了肝纤维化,确定YBX1是肝纤维化发展的关键因素.

关键词:
ATAC-seqq 的使用情况.染色体的可访问性 染色体的可访问性肝脏纤维化 肝脏纤维化Y盒结合蛋白 1 1 的结合蛋白

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