系统性血栓溶解随机化在内血管中风治疗中 (SHRINE) 合作:对SKIP和DEVT试验进行患者一级的综合分析
Raul G Nogueira1, Kazumi Kimura2, Yuji Matsumaru3
1Department of Neurology and Neurosurgery, University of Pittsburgh Medical Center Health System, Pittsburgh, Pennsylvania, USA raul.g.nogueira@icloud.com.
Journal of neurointerventional surgery
|June 8, 2023
概括
单独的内血管治疗 (EVT) 没有证明不劣于静脉血栓溶解 (IVT) 加EVT用于中风恢复. 然而,单独使用EVT可能有利于某些患有较长发病时间或特定动脉闭塞的患者.
科学领域:
- 神经学 神经学
- 干预心脏病学 干预心脏病学
- 公共卫生 公共卫生
背景情况:
- 内血管治疗 (EVT) 是急性缺血性中风的关键干预措施.
- 最优的策略包括单独比较EVT与静脉血栓溶解 (IVT),然后再进行EVT.
结论:
- 这些亚洲试验的当前数据并不能最终确定单独使用EVT与IVT+EVT组合相比,EVT的不劣.
- 个性化治疗决策可能是合理的,考虑诸如延长治疗开始时间和特定的闭塞类型等因素,以获得潜在的EVT单独益处.
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