患有急性缺血性中风的患者进行内血管血栓切除术的血栓迁移
ZeFeng Tan1,2, Lei Zhang3, Li'an Huang2
1Neurology, First People's Hospital of Foshan, Foshan, Guangdong, China.
Stroke and vascular neurology
|June 8, 2023
概括
预干预性血栓迁移 (TM) 不会改变急性中风中直接与桥梁内血管血栓切除 (EVT) 的结果. 然而,在大血管封闭患者中,TM与较低的完全再通道化率有关.
科学领域:
- 神经学 神经学
- 干预性放射学 干预性放射学
- 心血管医学 心血管医学
背景情况:
- 血管内血栓切除术 (EVT) 之前的血栓迁移 (TM) 是影响中风治疗结果的潜在因素.
- 干预前TM对直接EVT与桥梁EVT的比较疗效的影响尚不清楚.
研究的目的:
- 研究是否介入前的血栓迁移改变了直接EVT与桥梁EVT相比直接EVT的治疗效果.
- 分析TM对急性大血管封闭性中风患者的复血管化率和临床结果的影响.
主要方法:
- 一项多中心随机临床试验包括接受管血管造影检查急性大血管封闭的患者.
- 血栓迁移 (TM) 被放射科医生评估,在EVT之前分析成像差异.
- 主要结局是90天后修改的兰金级别 (mRS) 评分.
主要成果:
- 在包括的患者中,TM的发病率为11.3% (71/627).
- 患有TM的患者的完全再通道化率明显较低 (21.27%与36.23%,p=0.040).
- 在mRS轮班或0-1分数上,TM并没有显著改变直接与桥梁EVT的治疗效果.
结论:
- 介入前的血栓迁移不会改变前大血管阻塞中风中直接与桥梁EVT的功能结果.
- 血栓迁移与内血管血栓切除术前完全再通道化率的降低有关.
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