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Updated: Jul 27, 2025

Quantifying Agonist Activity at G Protein-coupled Receptors
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Published on: December 26, 2011

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六基诺林衍生物是粘附G蛋白结合受体ADGRG1/GPR56的选择性激动剂

Alexander L Vizurraga1,2, Michael J Robertson1,2, Maiya Yu1,2

  • 1Department of Pharmacology, University of Michigan School of Medicine, Ann Arbor, Michigan (A.L.V., M.Y., G.G.T.); and.

Molecular pharmacology
|June 8, 2023
PubMed
概括

研究人员确定了GPR56的新型小分子激动剂,这是一个关键的粘附G蛋白结合受体 (AGPCR). 这些强效化合物,包括化合物36.40,为了解GPR56功能提供了新的工具,并为癌症和神经系统疾病开发了治疗方法.

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