在青少年和年轻人中,获得医用大麻和长期使用阿片类药物
Kyungha Kim1, Rosalie L Pacula2, Andrew W Dick3
1Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
The American journal on addictions
|June 8, 2023
概括
在手术后,合法获得医用大麻并没有减少青少年和年轻人的长期阿片类药物使用. 这项研究强调了阿片类药物使用的潜在年龄差异,以及在这个脆弱群体中需要谨慎的处方管理.
科学领域:
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
- 青少年医学 青少年医学
背景情况:
- 阿片类止痛药的使用是一个重大问题,特别是手术后的长时间使用.
- 虽然医用大麻法律与成年人减少阿片类药物使用有关,但它们对年轻人群的影响仍未得到充分研究.
- 青少年和年轻人代表了阿片类药物依赖和不良结果的脆弱人口.
研究的目的:
- 调查医用大麻药房法律与青少年和年轻成人手术患者长期使用阿片类药物之间的关联.
- 为了确定与长期使用阿片类药物相关的因素,在这个特定的年龄组.
- 探索医用大麻作为阿片类药物替代品的疗效与年龄相关的潜在差异.
主要方法:
- 使用MarketScan®商业数据库 (2005-2014) 的回顾性队列研究.
- 包括195,204名12-25岁的患者,他们接受了13种手术之一.
- 通过处方数据定义的长期阿片类药物使用的分析及其与医用大麻法律和患者特征的相关性.
主要成果:
- 4.8%的研究人口经历了长期使用阿片类药物.
- 与长期使用阿片类药物的可能性增加显著相关的因素包括女性性别,更长的住院时间,更长的最初阿片类药物供应时间,农村居住和接受胆囊切除术.
- 在这种年龄组中,医用大麻药房法律的存在和长期使用阿片类药物的减少之间没有发现显著的关联.
结论:
- 与成年人不同的是,合法获得医用大麻与青少年和年轻人手术后长期使用阿片类药物减少无关.
- 这些发现表明,对有关阿片类药物使用的医用大麻政策的反应可能存在特定年龄的差异.
- 强调需要加强处方者监督和针对弱势年轻人群的阿片类药物使用量身定制的管理策略.
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