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Updated: Jul 27, 2025

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
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致死盒RNA螺旋酶eIF4A向的岩酸具有广泛的抗病原体潜力

Wiebke Obermann1, Mohammad Farhan Darin Azri2, Leonie Konopka1

  • 1Institute of Pharmaceutical Chemistry, Philipps University Marburg, Marburg, Germany.

Scientific reports
|June 8, 2023
PubMed
概括

洛卡格拉特是一种强大的eIF4A抑制剂,对各种真核病原体有着有前途的作用. 这项研究确定了rocaglate变体,并预测了它们对各种致病生物的有效性.

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