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Updated: Jul 27, 2025

Generation of In-Frame Gene Deletion Mutants in Pseudomonas aeruginosa and Testing for Virulence Attenuation in a Simple Mouse Model of Infection
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一个遗传开关控制了Pseudomonas aeruginosa的表面殖民活动

Christina Manner1, Raphael Dias Teixeira1, Dibya Saha1

  • 1Biozentrum, University of Basel, Basel, Switzerland.

Nature microbiology
|June 8, 2023
PubMed
概括

Pseudomonas aeruginosa 使用遗传开关来创建用于表面殖民和分散的专门细胞群. 针对这种HecE通路可以控制这种机会性病原体的感染.

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Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
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