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Updated: Jul 27, 2025

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
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卡皮卡 (CIC) 基质瘤突变与MAPK激活相关,以暴露潜在的治疗点

Sourat Darabi1, Joanne Xiu2, Timothy Samec3

  • 1Hoag Family Cancer Institute, Newport Beach, CA, USA.

Medical oncology (Northwood, London, England)
|June 8, 2023
PubMed
概括

(CIC) 基因突变在寡头质瘤中很常见,表明MAPK通路激活增加. 识别CIC突变可以指导向的MEK/MAPK抑制剂疗法,以改善质瘤患者的存活率.

关键词:
卡皮克瓦 (Capicua) 是一个古老的植物.临床瘤学临床瘤学质瘤是一种质瘤.这就是MAPKK的意思.分子瘤学分子瘤学针对性药物 针对性药物

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