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关于带血血液血液学参数参考间隔的印度观点
Keyur Sabnis1, Swati Ghanghurde2, Akash Shukla1
1Rajiv Gandhi Medical College, 400605, Thane, India.
BMC pediatrics
|June 8, 2023
概括
这项研究确定了印度孟买新生儿带血的第一个血液学参考间隔. 这些新的参考值对于准确的实验室数据解释和该地区的临床决策至关重要.
科学领域:
- 血液学 血液学 血液学
- 新生儿医学 新生儿医学
- 公共卫生 公共卫生
背景情况:
- 血液学参考间隔 (RIs) 随着高度,年龄和性别等因素而有显著变化.
- 准确的RI对于解释实验室数据和指导临床治疗至关重要.
- 印度目前缺乏新生儿带血血液血液学参数的确立RI.
研究的目的:
- 为印度孟买新生儿的带血建立规范性血液学参考间隔.
- 为准确解释该地区新生儿血液检测提供基线.
- 为了解决印度国家血液学参考数据的现有差距.
主要方法:
- 一项涉及127名在孟买出生的健康,满期新生儿的横截面研究.
- 在EDTA管中采集2-3毫升的带血样本.
- 使用非参数方法分析血液学参数,以确定95%的RIs.
- 使用曼·惠特尼U测试对各种人口和产科因素进行统计比较.
主要成果:
- 对于关键的血液学参数 (包括WBC,RBC,HGB,HCT,MCV,MCH,MCHC和血小板) 确立了95%的RI.
- 根据输送类型观察到WBC和某些白细胞差异 (EOS%,NEU,LYM,MON,BAS) 的统计学上显著差异.
- 没有发现基于婴儿性别 (MCHC除外) 或产科病史的显著差异.
结论:
- 在印度孟买成功建立了新生儿带血的第一个特定的血液学参考间隔.
- 导出的RI适用于孟买地区的新生儿.
- 建议进行更大规模的全国性研究,以制定全面的印度血液学参考间隔.
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