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Updated: Jul 27, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

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主要有缺陷的CD8

Ellie Taus1, Michael Y Shino2, F Javier Ibarrondo2

  • 1Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.

Journal of translational medicine
|June 8, 2023
PubMed
概括

在肺移植接受者中,mRNA疫苗的效果较差. 这项研究发现了CD8+ T细胞反应中的特定缺陷,这对于对抗感染和预防器官排斥至关重要. 需要提高免疫功能低下个体的疫苗有效性.

关键词:
COVID-19 mRNA 疫苗的使用情况细胞免疫力 细胞免疫力肺移植 肺移植 肺移植这就是SARS-CoV-2病毒.实体器官移植 实体器官移植

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