使用便携式设备与长期COVID综合征患者的六分钟步行测试相结合的通风动态:一项初步研究
Jéssica Gabriela Messias Oliveira1, Renan Pereira Campos2, Beatriz Luiza Pinheiro Alves Azevedo1
1Department of Pulmonology, Universidade do Estado do Rio de Janeiro (UERJ), Policlínica Piquet Carneiro, Avenida Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.
BMC research notes
|June 8, 2023
概括
长期COVID-19综合征患者经常由于动态膨胀和低呼吸储备而经历运动能力受损. 这些情况与周围呼吸道疾病有关,影响整体功能表现.
科学领域:
- 肺部医学 肺部医学
- 心血管呼吸系统生理学
- 纵向健康研究 纵向健康研究
背景情况:
- 长期COVID-19综合征 (LCS) 呈现出各种持续症状,包括对身体功能产生重大影响.
- 了解LCS运动不耐症的生理基础对于有效的康复至关重要.
研究的目的:
- 为了研究LCS患者的动态呼吸反应.
- 确定这些反应对功能性运动能力的影响.
主要方法:
- 使用螺旋计和呼吸系统振荡计 (RO) 进行休息肺功能评估.
- 用Spiropalm®装备的6分钟步行测试 (6MWT) 和心肺运动测试 (CPX) 来评估运动能力.
- 分析了通风参数和运动表现指标之间的相关性.
主要成果:
- 很大一部分LCS患者表现出异常的静止呼吸机制,包括增加的共振频率和反应率.
- 分别在12.5%和62.5%的参与者中观察到减少的呼吸储备 (BR) 和动态膨胀 (DH).
- 运动能力,以6分钟步行距离 (6MWD) 和氧气吸收峰值 (VO2峰值) 来衡量,与呼吸系统参数显著相关,特别是R4-R20和VO2峰值,这表明外围气道受影响.
结论:
- 动态高通胀和低呼吸储备是导致LCS运动表现下降的关键因素.
- 研究结果表明,长期COVID患者的运动能力受损与周围呼吸道疾病之间存在关联.
- 简单,便携式的呼吸和代谢系统可以有效地评估这些功能限制.
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