COVID-19疫苗接种对生殖年龄妇女月经周期模式的影响:一个多中心的观察性研究
Naina Kumar1, Neha Gangane2, Ipsita Mohapatra3
1Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Hyderabad, Telangana, India.
Current drug research reviews
|June 9, 2023
概括
包括COVISHIELD和COVAXIN在内的COVID-19疫苗接种与少数女性的临时月经周期变化和症状有关. 随着COVAXIN的使用,月经不规则更频繁,但大多数女性没有经历任何显著的变化.
科学领域:
- 生殖健康 生殖健康
- 疫苗学 疫苗学 疫苗学
- 流行病学 流行病学
背景情况:
- 包括COVISHIELD和COVAXIN在内的COVID-19疫苗是为了减轻大流行病的严重后果而开发的.
- 了解这些疫苗对妇女生殖健康的影响对于公共卫生至关重要.
- 这项研究侧重于COVID-19疫苗接种对印度妇女月经模式的影响.
研究的目的:
- 评估COVID-19疫苗接种对月经周期模式和相关症状的影响.
- 为了研究COVISHIELD和COVAXIN疫苗之间的潜在效果差异.
- 分析18-45岁妇女接种疫苗后的月经前后症状.
主要方法:
- 一项多中心的观察性研究,涉及6个印度研究所的5709名女性参与者.
- 通过在线和离线采访收集关于月经周期变化和疫苗接种后症状的数据.
- 分析包括与疫苗类型 (COVISHIELD与COVAXIN) 和之前的COVID-19感染的相关性.
主要成果:
- 5.8%的参与者报告了疫苗接种后的月经障碍,包括周期变化和出血不规则.
- 与COVISHIELD (5.3%) 相比,COVAXIN组 (7.2%) 的月经不规则和周期长度变化明显高于COVISHIELD组 (5.3%).
- 721名参与者经历了新的或恶化的月经前后症状,在科维希尔德组更为普遍.
结论:
- 在少数女性中,COVISHIELD和COVAXIN疫苗与月经障碍和症状有关.
- 随着COVAXIN的使用,月经不规则变得更加明显,尽管94.7%的人报告出血量没有变化.
- 建议进行长期研究,以确认疫苗对月经的影响是暂时的,不是严重的.
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