老年人性食道炎的患病率及其临床特征
Yasuhiro Fujiwara1, Atsushi Kanamori1, Akinari Sawada1
1Department of Gastroenterology, Osaka Metropolitan University, Abenoku, Japan.
Scandinavian journal of gastroenterology
|June 9, 2023
概括
高性食管炎 (EoE) 在老年人中不常见,在这项研究中,只有6%的65岁或以上的患者. 老年人中EoE的临床特征与年轻人相似.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 老年病的医生 老年病的医生
背景情况:
- 性食道炎 (EoE) 是一种慢性免疫介导的食道疾病.
- 中年男性的EoE患病率较高,老年人群的数据有限.
- 全球人口老龄化需要了解老年人的EoE.
研究的目的:
- 为了确定65岁及以上成年人中EoE的患病率.
- 描述老年人EOE的临床表现,组织学发现和治疗反应.
主要方法:
- 对前性生成的EoE患者数据库的回顾性分析 (2010年2月 - 2022年12月).
- 纳入标准:内镜检查,食道活检,以及≥15个乙素/HPF.
- 在临床,组织学和治疗参数上,老年人 (≥65岁) 与年轻人 (18-64岁) 成人队伍的比较.
主要成果:
- 在309名 (6.5%) 的EoE患者中,有20名年龄在65岁或以上.
- 老年患者表现出更高的医疗并发病率 (75%对38%,p=0.002).
- 纤维化没有显著差异;老年患者没有接受重复或维护局部类固醇治疗.
结论:
- 根据这一队列,EoE在老年人群中似乎不常见.
- 老年人EoE的临床特征与年轻患者相似.
- 需要进一步的前性研究来了解与年龄相关的趋势和老年人未来的患病率.
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