生物和植物化学潜力的生物和植物化学潜力
Micheli Negri Brusamarello1, Antonio Pedro Brusamarello2, Mário Antônio Alves da Cunha3
1Programa de Pós-Graduação em Biotecnologia, Universidade Tecnológica Federal do Paraná, Dois Vizinhos, Brazil.
Natural product research
|June 9, 2023
概括
这项研究发现,Baccharis trimera (Less.) 使用绿色化学制备的DC叶子提取物具有显著的抗氧化和抗菌特性. 这种具有成本效益的植物提取物显示出治疗猪肠病原体的潜力,降低了农业的生产成本.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 绿色化学 绿色化学
背景情况:
- 巴卡里斯·特里梅拉 (Baccharis trimera) (较少的) 是一个植物. DC 提取物具有抗氧化和抗微生物活性.
- 植物化学研究表明各种疾病的潜在治疗应用.
- 猪肠病原体在畜牧业生产中构成了重大挑战.
研究的目的:
- 为了研究B. trimera叶子提取物的化合物,抗氧化剂和抗菌活性.
- 为了评估水性B. trimera提取物对细菌菌株的植物化学潜力.
- 探索使用B. trimera作为猪的低成本预防剂.
主要方法:
- B. trimera 叶子的水性提取物,通过使用水作为溶剂来制.
- 使用二极管阵列检测 (HPLC-DAD) 的高性能液体染色学进行植物化学分析.
- 通过DPPH和ABTS激素清除试验评估的抗氧化活性.
- 对ATCC标准细菌菌株和猪临床分离物进行抗菌活性测试.
主要成果:
- 脱过程产生了富含化合物的提取物.
- 鉴定出高度的基,铁,咖啡酸和 cinnamic 酸.
- 这种提取物具有很高的清除DPPH和ABTS基的能力.
- 观察到针对格拉姆阴性细菌的显著抗微生物活性.
结论:
- B. trimera 水性提取物是具有强大的抗氧化活性的丰富的化合物来源.
- 提取物对包括猪肠道病原体在内的阴性细菌表现出有希望的抗微生物作用.
- 这种具有成本效益的绿色化学衍生提取物具有在猪群中预防性使用的潜力,有助于降低生产成本.
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