对患有糖尿病相关足的人进行卸载干预的有效性:系统性审查和元分析
P A Lazzarini1,2, D G Armstrong3, R T Crews4
1School of Public Health and Social Work, Queensland University of Technology, Brisbane, Queensland, Australia.
Diabetes/metabolism research and reviews
|June 9, 2023
概括
非可拆卸的卸载设备是最有效的治疗糖尿病相关的足部 (DFU). 虽然其他干预措施有希望,但需要更多高质量的试验来确认它们的有效性.
科学领域:
- 足科和伤口治疗治疗
- 糖尿病学 糖尿病学
- 生物医学工程 生物医学工程
背景情况:
- 与糖尿病相关的脚 (DFU) 需要有效的卸载才能愈合.
- 本系统性审查评估了DFU管理的各种卸载干预措施.
研究的目的:
- 系统地审查和评估DFU不同卸载干预措施的有效性.
- 根据临床结果和证据确定性,比较各种卸载方法.
主要方法:
- 在主要数据库 (PubMed,EMBASE,Cochrane) 进行系统的文献搜索.
- 包括对照性和非对照性研究,对14个临床问题的比较.
- 证据评估的元分析和GRADE方法.
主要成果:
- 与可拆卸设备相比,不可拆卸的卸载设备可能会改善的愈合.
- 手术干预 (切断,肌延长) 与卸载相结合,显示了特定DFU位置的潜力.
- 卸载设备在治愈DFU方面通常优于治疗鞋类,尽管证据确定性低至中等.
结论:
- 非可拆卸的卸载装置可能是脚部DFU最有效的.
- 外科辅助医生为特定的DFU地点提供好处,但证据确定性低至中等.
- 进一步进行高质量的试验至关重要,以加强对卸载干预措施的证据.
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