肥胖对呼吸道机械学的影响
Kumar Shanmugasundaram1, Geetanjali Bade1, Meghashree Sampath1
1Department of Physiology, All India Institute of Medical Sciences, New Delhi, India.
Indian journal of endocrinology and metabolism
|June 9, 2023
概括
肥胖显著影响肺功能,更高的腰比 (WHR) 和腰围 (WC) 在女性中表现出更明显的影响. 子周长 (NC) 没有显示肺机械的显著变化.
科学领域:
- 肺部医学 肺部医学
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 肥胖是已知的导致肺功能受损的因素之一.
- 以前的研究已经确定了肥胖和肺功能下降之间的联系.
研究的目的:
- 调查各种肥胖指数对健康成年人肺部机制的影响.
- 为了比较不同肥胖测量对呼吸功能的影响.
主要方法:
- 一项涉及45名健康受试者 (23名男性,22名女性) 的横截面研究.
- 测量包括人类参数 (BMI,WC,HC,NC,WHR) 和肺功能测试 (呼吸计,IOS,FeNO).
- 根据肥胖指数,分组分析了受试者.
主要成果:
- 在男性中,增加的WHR和BMI与更高的呼吸道阻力相关 (R5,R20).
- 在女性中,增加的WHR和WC与气道阻力和反应能力发生显著变化有关.
- 在女性中,更高的WC也与更低的FEV1/FVC比率相关.
结论:
- 肥胖和超重状态导致肺体积,容量和呼吸道机制发生显著变化.
- 更高的腰围 (WC) 和腰比 (WHR) 显著影响肺机械,特别是在女性身上.
- 子周长 (NC) 没有发现与肺机械学的变化有关.
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