短期作用的β型
Andrea Yu-Lin Ban1, Paranthaman Vengadasalam2, Sri Wahyu Taher3
1MB Bch BAO (Ireland), MMed (UKM), Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Kuala Lumpur, Malaysia.
概括
在马来西亚,过度处方高短效β2-激动剂 (SABA) 与较差的喘控制和更严重的喘恶化有关. 这突显了迫切需要更新的临床指南和政策干预措施,以改善喘管理.
科学领域:
- 肺部病理学 肺部病理学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 过度使用短效β2-激动剂 (SABA) 是喘管理中的全球关注.
- 了解SABA处方模式及其在各种医疗保健环境中的临床影响至关重要.
研究的目的:
- 为了评估马来西亚的SABA处方模式.
- 调查SABA处方频率与SABINA III队列中的喘控制和严重恶化之间的关联.
主要方法:
- 在马来西亚的初级和专科护理中心对731名患者 (≥12年) 进行了观察性,横截面研究.
- 收集了关于处方喘治疗,SABA处方和喘症状控制的数据.
- 多变量回归模型分析了SABA处方和喘结果之间的关联.
主要成果:
- 观察到SABA过度处方 (≥3处方/年) 的高患病率 (47.4%).
- 近10%的患者在没有处方的情况下购买了SABA,很大一部分人购买了多重吸入器.
- 处方≥3个SABA吸入器与部分控制喘的几率较低和严重恶化的几率较高有关.
结论:
- 在马来西亚,在不同的医疗保健机构中,SABA的过度处方是一个重大问题.
- 调查结果强调,医疗保健提供者和政策制定者需要实施基于证据的建议,以减轻SABA的过度使用.
- 解决SABA过度处方问题对于改善马来西亚的喘控制和减少恶化的情况至关重要.
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