在2型糖尿病患者中产生力量和激活膝盖延伸肌和肌的肌肉 2型糖尿病患者 患者
Samira Shahrjerdi1, Farid Bahrpeyma1, Hans H C M Savelberg2
1Department of Physical Therapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Journal of medical signals and sensors
|June 9, 2023
概括
2型糖尿病 (T2DM) 通过降低肌肉力量和改变对抗剂-激动剂肌肉相互作用,损害膝关节关节功能. 这项研究揭示了T2DM患者对抗性肌肉激活的减少,这表明神经适应维持神经肌肉功能.
科学领域:
- 神经肌肉生理学 神经肌肉生理学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 2型糖尿病 (T2DM) 与肌肉力量生成的减少有关.
- 这种缺陷可能源于激进肌肉和对抗肌肉激活模式的改变.
研究的目的:
- 为了研究T2DM对膝关节对抗肌肉和激动肌肉之间的相互作用的影响.
主要方法:
- 在T2DM患者和健康对照者之间比较了峰值扭矩,表面电动图 (SEMG) 根平方平均值 (RMS) 和扭矩/RMS比率.
- 在60°/s的同位运动同心收缩过程中记录了膝盖曲肌和延伸肌的SEMG.
- 使用独立的样本t测试进行统计分析,显著程度为0.05.
主要成果:
- 在T2DM患者中,在膝盖最大延伸 (P=0.010) 和曲 (P=0.022) 期间,对手肌肉激活显著降低.
- 在T2DM患者中观察到膝盖曲率 (41.3%) 和延伸扭矩 (49.1%) 的减少,以及较低的RMS值.
- 组之间没有发现扭矩/RMS比率的显著差异 (P > 0.05).
结论:
- 在T2DM中,膝盖延伸器和曲器扭矩的减少与肌电活动的减少相关.
- 在T2DM中较低的对抗剂/激动剂相互作用可能表明旨在维护神经肌肉功能的神经补偿机制.
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