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Updated: Jul 27, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

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复制病毒基因组诱导细胞应激反应,干扰病毒蛋白质表达,而不影响抗病毒免疫力

Carolina B Lopez, Lavinia J Gonzalez Aparicio, Yanling Yang

    bioRxiv : the preprint server for biology
    |June 9, 2023
    PubMed
    概括

    回复病毒基因组 (cbVGs) 通过PKR触发压力颗粒 (SG) 形成和翻译抑制,减少病毒蛋白表达,独立于MAVS信号. 在病毒感染期间,这种应激反应对于抗病毒免疫是不可或缺的.

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