聚基化学抗原受体识别指南治疗扩张的结构原理

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Updated: Jul 27, 2025

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

Published on: February 6, 2017

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Yi Sun, Tyler J Florio, Sagar Gupta

    bioRxiv : the preprint server for biology
    |June 9, 2023
    PubMed
    概括

    基化学抗原受体 (PC-CARs) 针对由人类白细胞抗原 (HLAs) 呈现的癌症被结构性分析. 这揭示了PC-CAR如何识别不同的HLA,指导有效的癌症免疫疗法的设计.

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    Diversity of Antigen Receptors01:28

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    Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
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