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Updated: Jul 27, 2025

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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在阿尔茨海默氏病的风险变体中存在阿尔茨海默氏病的风险变体

Holly N Cukier, Carolina L Duarte, Mayra J Laverde-Paz

    bioRxiv : the preprint server for biology
    |June 9, 2023
    PubMed
    概括

    一种新的阿尔茨海默氏病 (AD) 风险变体在三基因重复域3 (TTC3) 基因中影响神经元的发育和功能. 这种TTC3变体破坏了actin细胞骨架,导致细胞变化,可能有助于AD的发病.

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