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Updated: Aug 18, 2026

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一种基于病毒样粒子的双价PCSK9疫苗降低了非人类灵长类动物的LDL胆固醇水平

Alexandra Fowler1, Koen K A Van Rompay2, Maureen Sampson3

  • 1Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM USA.

bioRxiv : the preprint server for biology
|June 9, 2023
PubMed
概括

新型病毒样颗粒 (VLP) 疫苗向蛋白转化酶亚提利辛/素9型 (PCSK9) 有效降低LDL-C. 一种双价疫苗在没有他类药物的情况下显示出显著的胆固醇降低,突出显示出一种有前途的基于疫苗的方法.

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相关概念视频

Subviral Agents01:29

Subviral Agents

Subviral agents are infectious entities that resemble viruses but lack one or more viral components, such as a capsid or essential replication machinery. These agents include viroids, prions, and satellites, each possessing distinct structural and functional characteristics that influence their mode of infection and replication.Viroids are the simplest subviral agents, consisting of circular, single-stranded RNA molecules without a protein coat. They exclusively infect plants, relying entirely...