自闭症谱系障碍患者及其未受影响的生物学父母的感官运动行为
Erin K Bojanek1, Shannon E Kelly2, Lauren M Schmitt3
1University of Rochester, University of Rochester Medical Center.
Research square
|June 9, 2023
概括
自闭症谱系障碍 (ASD) 中的感觉运动障碍显示出不同的家族模式. 快速运动缺陷出现在没有更广泛的自闭症表型 (BAP) 特征的家庭中,而持续的运动问题与BAP特征有关.
科学领域:
- 神经科学是一个神经科学.
- 遗传学 是一个遗传学.
- 发展心理学 发展心理学
背景情况:
- 感官运动障碍在自闭症谱系障碍 (ASD) 中很常见,并且在未受影响的亲属中观察到,这表明它们是遗传风险的潜在内分类型.
- 这项研究调查了ASD不同运动行为和效应器系统中感觉运动障碍的家族性.
- 这项研究还研究了这些障碍与父母更广泛的自闭症表型 (BAP) 特征之间的关系.
结论:
- 快速感官运动行为在BAP试验者及其父母身上受到选择性的影响,这可能反映出自闭症特征独立于自闭症特征的ASD家族责任.
- 持续的感觉运动行为受到BAP+试验者和BAP-父母的影响,这表明与家族自闭症特征的联系,这可能与父母自闭症负债相结合时会产生风险.
- 这些发现突出了快速和持续的感觉运动变化作为自闭症风险的独特家族途径,与父母的自闭症特征独特地相互作用.
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