Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Principles of Disease Surveillance01:26

Principles of Disease Surveillance

136
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
136
Protein Networks02:26

Protein Networks

4.0K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.0K
Genomics02:02

Genomics

36.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.5K
Causality in Epidemiology01:21

Causality in Epidemiology

509
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
509
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

5.7K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.7K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.0K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Rethinking bioinformatics expertise in the era of artificial intelligence.

NPJ digital medicine·2026
Same author

Foundations of Gerophysics.

Aging·2026
Same author

Cell-Type-Resolved Pseudobulk Classification Across Independent Cohorts Identifies Microglial PTPRG as a Transcriptional Hub in Alzheimer's Disease.

bioRxiv : the preprint server for biology·2026
Same author

Longitudinal assessment of DNA repair signature trajectory in prodromal versus established Parkinson's disease.

NPJ Parkinson's disease·2025
Same author

The origin of septin ring size control in budding yeast.

The EMBO journal·2025
Same author

PEtab.jl: advancing the efficiency and utility of dynamic modelling.

Bioinformatics (Oxford, England)·2025

相关实验视频

Updated: Jul 27, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.3K

网络医学:促进对复杂疾病的新视角.

Marija Cvijovic1, Annikka Polster2

  • 1Department of Applied Mathematics and Statistics, University of Gothenburg, Gothenburg, Sweden.

Frontiers in bioinformatics
|June 9, 2023
PubMed
概括

复杂的疾病由于患者的变化而带来挑战. 一个新的模型将疾病负担视为状态载体,专注于个性化医学的个体特征.

科学领域:

  • 网络医学 网络医学
  • 系统生物学 系统生物学
  • 个性化医疗是个性化的医疗.

背景情况:

  • 复杂疾病在症状,进展和治疗反应方面表现出显著的患者间异质性.
  • 它们的发展涉及遗传,环境和心理社会因素之间的复杂相互作用.
  • 传统的疾病分类与重叠的机制和症状的同时出现作斗争.

研究的目的:

  • 为理解复杂疾病提出一种新的概念模型.
  • 将重点从诊断队列转移到个体患者的特征.
  • 促进对人类生理学和病理生理学的多维方法.

主要方法:

  • 概念化个体疾病负担作为状态载体.
  • 同时整合分子,生理和病理因素.
  • 研究重点转向确定个体的症状决定性特征.

主要成果:

  • 拟议的模型解决了疾病队列中个体间异质性的问题.
  • 它提供了一个理解健康和疾病之间缺乏明确区分的框架.
  • 它支持向更个性化的治疗策略迈进.

结论:

关键词:
复杂的疾病复杂的疾病.多维的患者表征.网络医学 网络医学鼻科 鼻科是指鼻科的学科.病理生理学 病理生理学

更多相关视频

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K
Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
07:46

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Published on: April 30, 2021

4.8K

相关实验视频

Last Updated: Jul 27, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.3K
A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K
Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
07:46

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Published on: April 30, 2021

4.8K
  • 一个新的状态向量模型为复杂疾病提供了新的视角.
  • 这种方法有助于理解个体疾病负担和异质性.
  • 它通过专注于患者特异性特征,推动了个人化医学的发展.