与非重症监护病房的COVID-19死亡率相关的临床特征和风险因素
Pierfrancesco Grima1, Marcello Guido2, Antonella Zizza3
1Infectious Diseases Unit, Vito Fazzi Hospital, Lecce, Italy.
Journal of preventive medicine and hygiene
|June 9, 2023
概括
高龄,慢性病和高流氧疗法预测住院COVID-19患者的死亡率. 这些发现有助于了解非ICU环境中的疾病进展和结果.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 关键护理医学 关键护理医学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 呈现出多样化的临床结果,严重病例需要住院治疗.
- 患者的人口统计学,并发病症和入院时的临床状况会影响预后.
研究的目的:
- 为了确定非重症监护室 (ICU) 住院的COVID-19患者的死亡率预测因素.
- 分析患者特征与医院治疗结果之间的关联.
主要方法:
- 对239名COVID-19患者的回顾性观察性研究,这些患者在早期的流行病浪潮中入院.
- 收集的数据包括人口统计,并发病,临床,实验室和放射学发现.
- 多变量逻辑回归分析了死亡率的预测因素.
主要成果:
- 平均年龄为67.8岁,57.3%的男性和73.6%的伴随性疾病.
- 死亡率为12.55%,平均住院时间为16.5天.
- 死亡率的独立预测因素包括老年 (OR 1.09),慢性病 (OR 4.04) 和需要高流氧治疗 (OR 18.23).
结论:
- 高龄,先前存在的慢性病和需要补充氧气是非ICU COVID-19患者死亡率的独立预测因素.
- 在死亡的患者中观察到更短的住院时间.
- 了解这些因素有助于改进对各个流行病波的回顾性分析和比较.
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