初始低剂量计算机断层扫描查结果和参与者特征摘要:基于最新的中国指南
Zixuan Zhang1, Yinyan Gao1, Shaohui Liu2
1Xiangya School of Public Health, Central South University, Changsha, China.
Frontiers in oncology
|June 9, 2023
概括
在使用低剂量计算机断层扫描 (LDCT) 查肺癌的个体中,超过四分之一的人没有达到指导标准. 这凸显了为肺癌查进行精细高风险人群选择的必要性.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 公共卫生 公共卫生
背景情况:
- 低剂量计算机断层扫描 (LDCT) 是肺癌早期检测的关键策略.
- 中国2021年肺癌查指南旨在识别高风险个体.
- 目前尚不清楚那些接受LDCT查的人是否遵守这些准则.
研究的目的:
- 根据2021年指南,评估中国人口中肺癌风险因素的分布.
- 评估LDCT查参与者是否遵守指南中定义的高风险标准.
- 为了告知未来的肺癌查目标人群选择.
主要方法:
- 在中国湖南的一家高等教学医院进行了横截面研究.
- 从2021年1月1日至12月31日期间接受LDCT的5486名参与者收集了数据.
- 描述性地分析了LDCT结果和基于指南的特征.
主要成果:
- 接受LDCT查的参与者的26.0%不符合指导方针定义的高风险标准.
- 这种不遵守甚至在36.4%的非吸烟者中也被观察到.
- 在84.3%的参与者中检测到肺结节,根据不同的截止值,阳性结节检测率从46.8%到71.2%不等.
- 与非吸烟男性 (21.8%) 相比,非吸烟女性 (26.7%) 的地面玻璃不透明度更为普遍.
结论:
- 接受LDCT查的很大一部分人不符合当前指南定义的高风险标准.
- 需要进一步的研究,以确定正确的肺结节的切断值.
- 为了有效的肺癌查,需要更精确和更局部的标准来识别高风险个体,特别是非吸烟女性.
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