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Updated: Aug 5, 2026

Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation
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打破构建:核酸纳米粒子 (NANPs) 的异热组装

Damian Beasock1, Anh Ha1, Justin Halman1

  • 1Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.

Bioconjugate chemistry
|June 9, 2023
PubMed
概括

工程核酸纳米粒子 (NANPs) 现在可以使用酶组装,为创建先进疗法提供了一种新方法. 这种核酶驱动的方法增强了NANP的功能和稳定性,用于治疗应用.

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相关概念视频

The Replisome03:01

The Replisome

DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...