相关实验视频

Updated: Jul 27, 2025

Studying Ribonucleotide Incorporation: Strand-specific Detection of Ribonucleotides in the Yeast Genome and Measuring Ribonucleotide-induced Mutagenesis
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Studying Ribonucleotide Incorporation: Strand-specific Detection of Ribonucleotides in the Yeast Genome and Measuring Ribonucleotide-induced Mutagenesis

Published on: July 26, 2018

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突变率之间的通用相互关系推动了基因组符合查加夫第二平价规则的基因组

Patrick Pflughaupt1, Aleksandr B Sahakyan1

  • 1MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK.

Nucleic acids research
|June 9, 2023
PubMed
概括

突变率解释了双链DNA (dsDNA) 中的查加夫第二平价规则 (PR-2),即使有链偏差. 这一发现揭示了基因组如何在进化时间尺度内实现PR-2合规.

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Combining Magnetic Sorting of Mother Cells and Fluctuation Tests to Analyze Genome Instability During Mitotic Cell Aging in Saccharomyces cerevisiae

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