来自六个的金氏化物的比较性特征
Yue-Guang Mi1,2, Xiao-Yan Xu1,2, Li-Li Hong1,2
1State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.
Journal of agricultural and food chemistry
|June 9, 2023
概括
这项研究描述了来自六种Panax植物的金色化物及其肠道微生物群代谢. 脱糖化是主要的途径,改变了金氏化物成分,突出了植物特异性的差异.
科学领域:
- 药理学 药理学是指药理学的学科.
- 自然产品 化学 化学
- 微生物学 微生物学
背景情况:
- 人参提取物广泛用于传统医学和补充剂.
- 了解人参酸的组成和新陈代谢对于它们的应用至关重要.
研究的目的:
- 从六种Panax植物物种中鉴定出人参酸的特征.
- 用小鼠肠道微生物群来比较它们的体外代谢概况.
- 为了研究人参酸的生物转化.
主要方法:
- 使用超高性能液态色谱/离子移动四极飞行时间质谱 (UHPLC/IM-QTOF-MS).
- 开发了定时多重反应监测 (sMRM) 用于量化.
- 在实验室内与大鼠肠道微生物群进行化.
主要成果:
- 在生物转化样本中鉴定了248种金氏化物/代谢物.
- 脱糖化是主要的代谢途径.
- 质帕纳克萨迪类型和油酸类型的沙因很容易被代谢.
- 在生物转化后,Panax物种之间的组成差异变得更加明显.
结论:
- 在肠道微生物群生物转化后,金色化物成分发生显著变化.
- 脱糖化是人参酸的关键代谢途径.
- 这项研究揭示了不同Panax物种的不同代谢概况和组成变异.
相关概念视频
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Halogens
Group 17 elements, known as halogens, are nonmetals. At room temperature, fluorine and chlorine are gases, bromine is a liquid, and iodine a solid. Astatine is a highly unstable radioactive element, so currently, most of its properties are unknown due to its short half-life. Tennessine is a synthetic element also predicted to be in this group.
Types of Chemical Bonds
Chemical bonding theories were pioneered by American chemist Gilbert N. Lewis. He developed a model called the Lewis model to explain the type and formation of different bonds. Chemical bonding is central to chemistry; it explains how atoms or ions bond together to form molecules. It explains why some bonds are strong and others are weak, or why one carbon bonds with two oxygens and not three; why water is H2O and not H4O.
Polar Covalent Bonds
Covalent bonds are formed between two atoms when both have similar tendencies to attract electrons to themselves (i.e., when both atoms have identical or fairly similar ionization energies and electron affinities). Nonmetal atoms frequently form covalent bonds with other nonmetal atoms. For example, the hydrogen molecule, H2, contains a covalent bond between its two hydrogen atoms. When two separate hydrogen atoms with a particular potential energy approach each other, their valence orbitals...
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Properties of Organometallic Compounds
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.


