相关实验视频

Updated: Jul 27, 2025

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

Published on: January 26, 2019

英国D68肠道病毒 (EV-D68) 传播的变化是从血清流行数据推断出来的

Margarita Pons-Salort¹, Ben Lambert², Everlyn Kamau³

¹MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, United Kingdom.

|June 9, 2023

概括

肠道病毒D68 (EV-D68) 感染显著增加,但广泛的先前免疫力表明神经病原性增加,解释了2014年儿童急性软骨髓炎 (AFM) 爆发.

科学领域:

病毒学病毒学
流行病学流行病学
公共卫生公共卫生

背景情况:

肠道病毒D68 (EV-D68) 在2014年在全球范围内出现,导致儿童急性软骨髓炎 (AFM).
驱动EV-D68出现的因素及其与AFM的关联仍然不清楚.

研究的目的:

调查EV-D68传染性和人口易感性的变化.
了解EV-D68的流行病学及其与AFM爆发的联系.

主要方法:

针对EV-D68特异性中和抗体的血清流行率在2006年,2011年和2017年的英语血清样本中测量.
用催化数学模型来估计感染概率的变化.

主要成果:

据估计,在研究期间,EV-D68感染的年概率增加了约50%.
血清发病率数据表明,在AFM爆发之前,EV-D68的广泛流通.
仅仅增加传播并不能完全解释AFM病例的数量.

结论:

仅仅是EV-D68传播和人口敏感性的变化无法解释2014年AFM爆发的原因.
神经病原性增加可能是解释EV-D68相关AFM的出现所需的.
肠道病毒的表型变化显著影响疾病流行病学.

关键词:

肠道病毒 D68 的病毒.流行病学流行病学全球卫生健康全球卫生健康数学模型是一个数学模型.血清流行病学病毒病毒病毒病毒.

更多相关视频

Measurement of γHV68 Infection in Mice

Measurement of γHV68 Infection in Mice

Published on: November 22, 2011

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. I. Collection of Virus Samples

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. I. Collection of Virus Samples

Published on: March 28, 2015

相关概念视频

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...

Principles of Disease Surveillance

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...