在LAAC后症状与非症状设备相关的血栓:来自多中心EUROC-DRT注册表的子分析
Vivian Vij1, Ignacio Cruz-González2, Roberto Galea3
1Department of Cardiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
概括
在左心房附带关闭 (LAAC) 后,与设备相关的血栓 (DRT) 构成中风或全身栓塞 (SE) 的重大风险. 在DRT患者中确定这些事件的预测因素对于改善患者的治疗结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 血栓形成研究研究
背景情况:
- 在左心房附带关闭 (LAAC) 后,与设备相关的血栓 (DRT) 与缺血性中风和全身栓塞 (SE) 等不良事件有关.
- 关于中风/SE预测因子的数据有限,特别是在LAAC后发展DRT的患者中.
研究的目的:
- 为了确定在LAAC后被诊断为DRT的患者中风/SE的诱导因素.
- 分析中风/SE事件与DRT诊断之间的时间关系.
主要方法:
- 分析了EUROC-DRT注册表,包括176名LAAC后DRT患者.
- 患有症状的DRT (与DRT诊断发生的中风/SE) 的患者与无症状的DRT患者进行了比较.
- 评估了基线特征,抗血栓策略,设备定位和事件时间.
主要成果:
- 14.2%的DRT患者 (25/176) 经历过中风/SE (症状性DRT).
- 卒中/SE发生在LAAC后198天的中位数,其中45.8%发生在DRT诊断后一个月内.
- 有症状的DRT患者表现出较低的射出分数和较高的非心房动率;事件时间不同,并且发生在不同的抗血栓治疗方案中.
结论:
- 在DRT患者中,中风/SE事件发生时与DRT诊断和独立发生.
- 鉴定DRT患者中风/SE的特定风险因素仍然具有挑战性,这表明所有这些患者的风险很大.
- 需要进行进一步的研究,以制定降低DRT和随后缺血事件的风险的策略.
相关概念视频
01:29Venous Thrombosis III: Interprofessional Care
11
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
11
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
38
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
38
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
16
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
16
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
43
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
43
01:30Acute Coronary Syndrome III: Diagnostic Studies
11
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
11