在mRNACOVID-19疫苗接种后患有心肌炎的患者的左心室功能的纵向评估
Barresi Nv1, S McCollum2, E Faherty3
1Yale University School of Medicine, 20 York Street, New Haven, CT, 06510, USA. nicholas.v.barresi@gmail.com.
Pediatric cardiology
|June 9, 2023
概括
接种mRNACOVID-19疫苗后的心肌炎可能导致亚临床心肌损伤. 随着时间的推移,左心室纵向菌株 (LVLS) 改善,表明受影响个体的恢复和风险分层的潜力.
科学领域:
- 心脏病学 心脏病学
- 疫苗学 疫苗学 疫苗学
- 医疗成像医学成像
背景情况:
- 肌心炎是mRNA COVID-19疫苗已知的并发症.
- 有限的数据存在于亚临床心肌损伤的长期影响,特别是左心室纵向菌株 (LVLS),接种疫苗后.
研究的目的:
- 纵向评估与疫苗相关的心肌膜炎患者的左心室 (LV) 功能.
- 评估随时间推移的射出分数 (EF),分数缩短 (FS),LVLS和透缩参数.
主要方法:
- 在mRNACOVID-19疫苗接种后被诊断患有心肌炎的20名患者的回顾性审查.
- 在初始呈现,12天和44天进行心声学.
- 使用标准和专用软件分析EF,FS,LVLS和透气功能.
主要成果:
- 该队列主要是青少年男性 (85%) 患有轻度心肌炎.
- 左心室纵向应变 (LVLS) 从初始呈现到随访显著改善 (p=0.004).
- 虽然喷射分数保持稳定,但LVLS表明心肌功能正在演变.
结论:
- 左心室纵向应变 (LVLS) 在mRNACOVID-19疫苗接种后心肌炎患者的纵向改善.
- 在这个人群中,LVLS作为亚临床心肌损伤和风险分层的有价值标志物.
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