水病死亡率和临床表现的危险因素
Salma Triana-González1, Cristina Román-López1, Stefan Mauss2
1Infectious Diseases Department, Hospital de Infectología 'Dr Daniel Méndez Hernández' La Raza National Medical Center.
AIDS (London, England)
|June 9, 2023
概括
墨西哥的Mpox死亡风险因素包括CD4细胞计数低,缺乏HIV治疗,以及大量的皮肤病变. 先进的艾滋病毒疾病与较高的mpox死亡率有关.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 麻疹 (原名麻疹) 是一种病毒性疾病,可能导致严重疾病和死亡.
- 晚期艾滋病毒感染的人有更高的严重mopox结果的风险.
- 了解mopox风险因素对于有效的公共卫生干预至关重要.
研究的目的:
- 为了确定mopox感染患者的死亡风险因素.
- 描述墨西哥一家参考医院mpox患者的临床特征.
主要方法:
- 从2022年9月到12月进行了前性队列研究.
- 包括72名确诊mopox的患者,收集了详细的流行病学,临床和生化数据.
- 随访一直持续到医院出院或死亡.
主要成果:
- 在72名患者中,88.9%是艾滋病毒感染者,98.6%是男性.
- 总体死亡率为6.9%. 在PWH中,死亡率为6.3%.
- 死亡风险因素包括CD4细胞计数≤100细胞/μl,没有抗逆转录病毒治疗和≥50个皮肤病变.
结论:
- 在PWH和非HIV患者中,Mpox的临床表现类似.
- 在mopox患者中的死亡率与先进的艾滋病毒疾病有关.
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