针对早期严重精神疾病的移动交互式肥胖治疗方法的调整:混合方法实施和试验随机对照试验的协议
Ginger E Nicol1, Madeline O Jansen2, Amanda R Ricchio1
1Department of Psychiatry, Washington University School of Medicine, Washington University in St. Louis, Saint Louis, MO, United States.
JMIR research protocols
|June 9, 2023
概括
这项研究适应了移动健康干预措施,以预防严重精神疾病 (SMI) 患者的肥胖. 调整后的干预措施在现实环境中显示出早期肥胖管理的前景.
科学领域:
- 公共卫生 公共卫生
- 数字健康数字健康
- 心理健康干预 心理健康干预
背景情况:
- 在患有严重精神疾病 (SMI) 的人群中,肥胖很普遍,显著减少了寿命.
- 目前的减肥治疗在这个人群中效果较差,这凸显了预防和早期干预策略的必要性.
研究的目的:
- 适应和试点测试移动健康 (mHealth) 干预措施,以预防早期SMI和I类肥胖 (BMI 30-35) 个体的肥胖.
- 在现实临床环境中利用1型混合研究设计进行干预适应和可行性测试.
主要方法:
- 选择了基于证据的SMS短信干预措施,以使用基于证据的干预措施的改进和修改报告的增强框架进行适应.
- 采用创新团队的方法,根据利益相关方 (管理人员,临床医生,患者) 在社区心理健康和俱乐部设置中的投入,确定必要的调整.
- 进行了一项随机的试点和可行性试验,将适应干预与6个月的注意力控制进行比较,并进行了3个月的延长阶段,评估体重,BMI和行为结果.
主要成果:
- 获得机构审查委员会对所有研究目标的批准.
- 到目前为止,在目标1和2的重点小组中招募了72名参与者,在试点和可行性试验 (目标3) 中招募了52名参与者.
结论:
- 成功应用了以证据为基础的框架来调整和规划mHealth干预措施的可行性测试,以预防早期SMI中的肥胖.
- 这项研究旨在将技术整合到社区心理健康环境中,以促进身体健康并预防早期精神疾病患者的肥胖.
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